To purchase short term access, please sign in to your Oxford Academic account above. Register, Oxford University Press is a department of the University of Oxford. Dengue fever is a mosquito-borne tropical disease caused by the dengue virus. Immune Computation and COVID-19 Mortality: A Rationale for IVIg. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide, This PDF is available to Subscribers Only. The current record-breaking outbreak of dengue in Bangladesh, and other Asian countries, is a nightmare for any nation. Don't already have an Oxford Academic account? A person infected by the dengue virus develops severe flu-like symptoms. Fatigue is common during the acute stages of dengue infection (Kularatne, 2005, Schwartz et al., 1996, Zhang et al., 2005, Wittesjo et al., 1993) and is defined by the presence of a persistent sense of exhaustion that result in a decreased capacity for physical and mental work … About Transactions of the Royal Society of Tropical Medicine and Hygiene, Copyright © 2021 Royal Society of Tropical Medicine and Hygiene. Dengue has associated with a wide variety of chronic symptoms (depression, insomnia, fatigue, headache, arthralgias, among others) which have … The disease, also called 'break-bone' fever affects infants, children and adults alike and can rarely be fatal. You could not be signed in. 14 Mild to moderate elevation of transaminases is seen in both dengue fever and dengue hemorrhagic fever. In dengue-endemic regions such as in Asia, misdiagnosis between COVID-19 and dengue can be highly problematic and could affect management of these diseases. In the Western Hemisphere, the Aedes aegypti mosquito is the most common transmitter of dengue infection; transmission by the Aedes albopictus mosquito bite has also been reported. Although the acute manifestations of dengue are well known, few studies have assessed the long-term consequences of dengue infection. By continuing you agree to the use of cookies. Nausea, vomiting, fatigue, rashes on face and limbs, mild bleeding and low blood pressure are other symptoms of dengue. Post-infection fatigue is an underappreciated burden of this widely prevalent infection. One hundred twenty-seven patients, 71 (55.9%) males and 56 (44.1%) females, of mean age 36.06 years (range, 16–70; S.D., 13.722), participated in this study. JOHNSON B.W. A follow-up telephone interview was performed two months following hospital discharge, where a Fatigue Questionnaire was administered. Talk to our Chatbot to narrow down your search. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin rash. Symptoms typically begin three to fourteen days after infection. Dengue patients had a significantly higher risk of fatigue at 2 months after the acute infection (RR 4.93 [95% confidence interval {CI} 2.3 to 10.4], p<0.001). Please check for further notifications by email. Females with dengue infection were more likely to have fatigue than males (RR 2.45 [95% CI 1.24 to 4.86], p<0.05). Risk was higher in dengue patients (vs non-dengue; relative risk [RR] 4.93 [95% confidence interval {CI} 2.3 to 10.4]) and more so in female dengue patients (vs male dengue patients; RR 2.45 [95% CI 1.24 to 4.86]). Als Chronic Fatigue Syndrome (CFS) bezeichnen Mediziner eine schwerwiegende und vielgestaltige neuroimmunologische Erkrankung (neuroimmunologisch = Nerven- und Immunsystem betreffend). En. Severe dengue, including dengue hemorrhagic fever or dengue shock syndrome, is characterized by severe abdominal pain, persistent vomiting, rapid breathing, bleeding gums, fatigue, restlessness, and blood in vomit, and may be fatal due to plasma leakage, fluid accumulation, respiratory distress, severe bleeding, or organ impairment. DF is characterized by fever, headache, arthralgia, retro-orbital pain, and skin rashes. In Europa und den USA gehört das Dengue-Fieber heute aufgrund der gesteigerten Reisetätigkeit zu den häufig importierten Infektionen bei Fernreisenden. Dengue-Fieber wird vom Dengue-Virus verursacht, das in vier verschiedenen Varianten (Serotypen) vorkommt: DENV 1-4. Your comment will be reviewed and published at the journal's discretion. Das Virus wird durch den Stich einer Stechmücke übertragen und ist in tropischen und subtropischen Gebieten verbreitet. In dengue, a vector-born disease caused by aedes aegypti mosquito, a person runs high fever, suffers red rashes on skin, pain behind eye sockets, joint pain and in serious case internal bleeding which can prove fatal. CHATURVEDI U.C. et al. Daneben weisen die Betroffenen noch verschiedenste weitere Beschwerden auf. Diese Mücken kommen hauptsächlich in städtischer Umgebung beziehungsweise generell in von Menschen besiedelten Regionen vor. Full size image. May 2005:639-652. Recovery generally takes two to seven days. In multivariate analysis, increased age, female sex, the presence of chills, and the absence of rashes were significantly associated with the development of fatigue post-dengue infection. Although there is no specific treatment for dengue, … This is not simply fatigue and apathy, as in the case of flu, but a generalized pain throughout the body and a strong feeling of … It results when a person who is already infected with the dengue virus gets another infection from a different dengue virus. Check the full list of possible causes and conditions now! This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (. This is mainly because approximately 80% of COVID-19 cases are mild to moderate cases with unspecific symptoms and mimic dengue (Henrina et al., 2020). Within the literature, there is variation regarding the reported proportion of cases (2–68%) experiencing post-acute consequences of dengue infection (such as fatigue, asthenia and trouble working), as well as the reported duration of these symptoms [ 48 ]. Symptoms of dengue are sudden high fever, severe headaches, pain behind the eyes, severe muscle and joint pain, fatigue… Up to 50-100 million infections are now estimated to occur annually in over 100 endemic countries, putting almost half of the world’s population at risk. 2005 Oct; 43(10):4977-4983. Es existieren vier verschiedene Serotypen (Untergruppen) des Virus, die innerhalb der letzten 2000 Jahre in Asien sehr wahrscheinlich unabhängig voneinander von nichtmenschlichen Primaten auf den Mens… The general malaise associated with dengue fever is accompanied by severe pain in joints and muscles, which are present for several days. However, some patients with DF develop post-dengue fatigue syndrome (PDFS) following their initial febrile episode. Fatigue, Restless and Irritable; Intense Stomach Pain; Vomiting (minimum thrice in one day) Dengue symptoms in children. Don't already have an Oxford Academic account? Dengue-Fieber ist eine meldepflichtige Infektionskrankheit. Shock occurs after 2 – 6 days if the patient remains untreated, … In acute cases, decreased urine … There was no significant association between fatigue and dengue severity. The incidence of dengue has increased 30-fold over the last 50 years. Corresponding author: Present address: Department of Parasitology, Faculty of Medicine, University of Colombo, No. Common symptoms of COVID-19 are high fever, breathlessness, cough, body fatigue and loss of sense of smell and taste. : Serotype-Specific Detection of Dengue Viruses in a Fourplex Real-Time Reverse Transcriptase PCR Assay; J Clin Microbiol. Post-infectious fatigue syndrome in dengue infection ... IgM to dengue were considered as evidence of acute dengue infection (Innis et al., 1989). Dengue shock syndrome This is a serious complication of dengue fever. A number of other tropical infections are also known to cause post-infectious fatigue syndromes and this highlights the importance of including questions about overseas travel when a diagnosis of ME/CFS is being … A very high temperature in children can sometimes lead to fits or convulsions. Twenty-five (19.7%) patients had dengue haemorrhagic fever and the remaining 102 (80.3%) had dengue fever. Deciphering the Role of Human Gastrointestinal Microbiota in the Pathogenesis of Vaginal Infection and Cervical Cancer. For instance, symptoms that are exclusive to dengue include vomiting, swollen glands, rashes, and vomiting. This study aimed to evaluate the prevalence and associations of post-infection fatigue in dengue patients compared with non-dengue fever patients. : Dengue vaccines: Problems & prospects: Indian J Med Res 121. 15 found hospitalized dengue patients with persistent fatigue were older on average (aged 39±13 y) than those with no persistent symptoms (aged 35.11±13.87 y, p=0.006; OR 1.118, 1.033 to 1.209). Hauptsymptome sind eine lähmende geistige und körperliche Erschöpfung und Müdigkeit, die sich nicht durch eine bekannte körperliche Ursache oder spezifische psychische Störung erklären lassen. Parkash et al. Dabei sollten speziell für die Tropen entwickelte Repellents (etwa mit … Ta. If you originally registered with a username please use that to sign in. Novel Approaches of CRISPR-Cas Technology in Airway Diseases. Please check your email address / username and password and try again. Verwendung von Repellents: Das sind insektenabweisende Hautlotionen und -sprays. We prospectively studied the incidence and factors associated with fatigue in a cohort of patients following dengue infection. Chronic Fatigue Syndrome & Dengue Fever Symptom Checker: Possible causes include Infectious Mononucleosis. Zika vs. Dengue: symptoms and diagnosis. Copyright © 2021 Elsevier B.V. or its licensors or contributors. Although dengue fever is already well recognised to be a cause of prolonged debility this is the first research paper to look at the development of a more specific post-infectious fatigue syndrome. Auf Facebook teilen Auf Twitter teilen Bei Pinterest pinnen Drucken Per WhatsApp teilen. Die einzigen bekannten Wirte des Virus sind Primaten und verschiedene Stechmückenarten. For full access to this pdf, sign in to an existing account, or purchase an annual subscription. Severe dengue patients had a higher mean fatigue score (p=0.024). Most users should sign in with their email address. Allesamt werden von der Aedes-Mücke übertragen: am häufigsten von der Gelbfieber- oder Tigermücke (Aedes aegypti oder Stegomyia aegytpi), manchmal auch von der asiatischen Tigermücke (Aedes oder Stegomyia albopictus). Dengue is a mosquito-borne disease caused by any one of four dengue viruses. Liver is a frequently involved organ in dengue infection. In case of severe dengue, the patient is likely to experience severe abdominal pain, persistent vomiting, rapid breathing, bleeding gums, fatigue, restlessness, and blood in vomit. We included patients with serologically confirmed dengue infection admitted to the National University Hospital, Singapore, during a dengue outbreak from October–November 2005. The development of dengue shock syndrome with consequent multi-organ failure proves fatal. Mr. Bn. In some patients, dengue virus RNA was performed by reverse transcriptase-nested PCR (Lanciotti et al., 1992). Host factors, such as age and sex may be important in the pathogenesis of this clinical entity. Dengue haemorrhagic fever (DHF) is a complication of dengue fever that tends to affect children under 10 years or age or older adults. 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Post-infection fatigue and its demographic and clinical associations were assessed in adult dengue and non-dengue fever patients 2 months after the acute infection in a prospective cohort study in Sri Lanka. Our findings are useful to triage patients at risk of fatigue for follow-up. Search for other works by this author on: Department of Clinical Medicine, Faculty of Medicine, University of Colombo, Department of Clinical Medicine, Faculty of Medicine, General Sir John Kotelawala Defence University, Centre for Dengue Research, Faculty of Medical Sciences, University of Sri Jayewardenepura, Department of Pathology, School of Medical Sciences, University of New South Wales, Sydney. Symptoms of dengue in children and those who have acquired the disease for the first time may be mild. Dengue is a mosquito-borne viral infection causing a severe flu-like illness and, sometimes causing a potentially lethal complication called severe dengue. The severity of dengue was graded as dengue fever, dengue haemorrhagic fever and dengue shock syndrome. This observation represents the first systematic evidence that dengue can result in clinical disease beyond the acute phases of infection. Copyright © 2006 Elsevier B.V. All rights reserved. 11 –13 If a dengue patient complains of abdominal pain, nausea, vomiting and anorexia, liver involvement should be suspected. Onmeda-Newsletter! DHF starts abruptly with continuous high fever and headache. Often, there are associated respiratory and intestinal symptoms such as sore throat, cough, nausea, vomiting, and abdominal pain. Dengue symptoms in children are almost the same as in the young and in adults. Teixeira et al. Significance was assessed at P < 0.05. 25, Kynsey Road, Colombo 8, Sri Lanka; Tel: +94 112 695 300; E-mail: © The Author(s) 2020. Previous studies on post-infection fatigue in dengue are few but suggest that up to 25% of dengue patients may suffer from fatigue. Restlessness. Around 400 million dengue infections occur across the globe each year. Dengue infection during the 2006 epidemic was established in these individuals by the presence of anti-dengue IgM and a high titer of anti-dengue IgG (≥1280), in the absence of clinical symptoms (Pupo et al., unpublished data).16, 17. We use cookies to help provide and enhance our service and tailor content and ads. et al. The presence of significant fatigue was considered as the main outcome measure. Other symptoms and signs of Dengue fever . हिं . Of 260 patients, 158 had dengue and, of these, 51 (32%) had fatigue at 2 months.

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